Colin E. Champ, MD

  • Clinical Assistant Professor, Radiation Oncology
  • Physician, UPMC St. Margaret

I am a radiation oncologist and clinical assistant professor at the UPMC CancerCenter/University of Pittsburgh at UPMC St. Margaret. I am dually board-certified in radiation oncology and integrative medicine, and my research interests include the prevention and treatment of cancer with lifestyle modification, including exercise and dietary modification. I have published extensively and have been asked to lecture on these topics all over the world. I am also actively involved in resident teaching and mentorship.

Teaching Activities

  • Project advisor for the University of Pittsburgh Department of Chemical Engineering Ph.D. program. The project is developing a nano-sized device that monitors ketosis.
  • Medical Project Advisor for Carnegie Mellon University Rapid Prototyping Course. The undergraduate and graduate student class built a “tracking” device that monitored patient activities while at home to help medical personnel care for patients remotely.

Education & Training

  • MD: Jefferson Medical College, Philadelphia, PA
  • Residency: Jefferson Medical College, Philadelphia, PA

Representative Publications

Champ CE, Smith RP. Radiation Recall and Woody Fibrosis. New England Journal of Medicine. 372;20. May 14, 2015

Champ CE, Joshua D. Palmer JD, Volek JS, Werner-Wasik M, Andrews DW, Evans JJ, Glass J, Kim L, Shi W.  Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme.  Journal of Neuro-Oncology. J Neurooncol. 2014 Mar;117(1):125-31.  

Champ CE, Francis L, Klement RJ, Dickerman R, Smith RP. Fortifying the Treatment of Prostate Cancer with Physical Activity. Prostate Cancer. 2016;2016:9462975.

Champ CE, Klement RJ. Commentary on “Strong adverse prognostic impact of hyperglycemic episodes during adjuvant chemoradiotherapy of glioblastoma multiforme.” Strahlenther Onkol. 2014. [epub ahead of print].

Klement RJ, Champ CE.  Calories, carbohydrates, and cancer therapy with radiation: exploiting the five R’s through dietary manipulation. Cancer Metastasis Rev. 2014:1-13.

Klement RJ, Champ CE, Otto C, Kämmerer U. Anti-tumor effects of ketogenic diets in mice: A meta-analysis. PLOS One. PLoS One 11, e0155050 (2016)

Nowak K, Eldredge-Hindy H, Champ CE.  Metformin: The sweet link between tumor genetics and metabolism?  OA Cancer. 2014 Apr 09;2(1):7.

Mishra MV, Champ CE, Keith SW, Showalter TN, Anne PR, Bar-Ad V.  Conditional survival probabilities in patients with resected pancreatic carcinoma: A population-based analysis.  Am J Clin Oncol. 2014 Apr;37(2):107-11.

Siglin J, Champ CE, Zaorsky N, Vakhnenko Y, Witek ME, Harrison A, Shi W.  Optimizing Patient Positioning for Intensity Modulated Radiation Therapy in Hippocampal-Sparing Whole Brain Radiation Therapy.  Practical Radiation Oncology. 2014 January 14

Palmer JD, Siglin J, Yamaoah K, Champ CE, Bar-Ad V, Werner-Wasik M, Evans JJ, Kim L, Glass J, Farrell C, Andrews DW, Shi W. Re-resection for recurrent high-grade glioma in the setting of re-irradiation: more is not always better. J Neurooncol. 2015 May 30.

Shi W, Jain V, Kim H, Champ CE, Jain G, Farrell C, Andrew DW, Judy K, Liu H, Artz G, Werner-Wasik M, Evans JJ. Fractionated Stereotactic Radiotherapy for Facial Nerve Schwannomas. J Neurol Surg B Skull Base. 2016 Feb;77(1):75-80.

Research Interests

I currently have a four-part trial underway that uses activity trackers worn by patients before, during, and after radiation therapy to track the change in activity levels from treatment for breast, prostate, lung, and head and neck cancer. The breast cohort has completed, and we have found a minimal change in activity levels in these patients. This data is currently being written for publication.